BDBM310811 US10150766, Example 2

SMILES Cc1nc2C3CCCC(Cc2c(n1)-c1ccn[nH]1)N3C(=O)c1cccc(c1Cl)C(F)(F)F

InChI Key InChIKey=VCVAMSJVHFXALX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310811   

TargetP2X purinoceptor 7(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310811(US10150766, Example 2)
Affinity DataKi:  22.4nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent