BDBM31084 1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methyl-phenyl)urea

SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]nc(N)c23)c1

InChI Key InChIKey=MPVGZUGXCQEXTM-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 31084   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Lanzhou University Second Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31084BDBM31084(1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-...)
Affinity DataIC50: 95nMAssay Description:Inhibition of RIPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Lanzhou University Second Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31084BDBM31084(1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-...)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to RIPK1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Lanzhou University Second Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31084BDBM31084(1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of RIPK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed