BDBM31106 2-substituted indole-3-carboxylate, 27c

SMILES COC(=O)c1c(Nc2ccc(Cl)cc2)[nH]c2ccccc12

InChI Key InChIKey=UOKONIXFLRFLAF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31106   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Friedrich Alexander University Erlangen

LigandPNGBDBM31106(2-substituted indole-3-carboxylate, 27c)
Affinity DataIC50: 9.80E+3nM EC50:  7.20E+3nMpH: 7.4 T: 2°CAssay Description:For determination of the activity of 5-LO in 40000g supernatant (S40), aliquots of the supernatants were added to reaction mix, and were preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed