BDBM31111 2-substituted indole-3-carboxylate, 27h

SMILES COC(=O)c1c([nH]c2ccccc12)N(CC=C)CC=C

InChI Key InChIKey=VOAOXYYRHVDNNJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31111   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Friedrich Alexander University Erlangen

LigandPNGBDBM31111(2-substituted indole-3-carboxylate, 27h)
Affinity DataIC50: 6.90E+3nM EC50:  1.25E+4nMpH: 7.4 T: 2°CAssay Description:For determination of the activity of 5-LO in 40000g supernatant (S40), aliquots of the supernatants were added to reaction mix, and were preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed