BDBM311131 US10155751, Example 18
SMILES CC(C)n1cc(cn1)-c1cc(O[C@H](C)[C@H]2CNC(=O)C2)c2c(C)n(C)nc2c1
InChI Key InChIKey=FHFPLTHIIFJBBX-GDBMZVCRSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 311131
TargetTyrosine-protein kinase SYK [342-635](Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 1.10nMAssay Description:Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3 [564-960](Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 4.67E+3nMAssay Description:Recombinant human FLT3 (amino acids 564-958, Molecular weight 48.6 kDa, Invitrogen #PR4666C) was expressed with an Histidine tag. The test compounds...More data for this Ligand-Target Pair
Affinity DataIC50: 2.02E+4nMAssay Description:Recombinant human Aurora B (amino acids 1-344, clone number DU1773, Molecular weight 40.2 kDa, University of Dundee) was expressed as a fusion protei...More data for this Ligand-Target Pair