BDBM311863 US10155972, Compound Incyte 1

SMILES Nc1nonc1\C(Nc1cc(F)cc(Cl)c1)=N/O

InChI Key InChIKey=QEEAODKJQVGRMU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 311863   

TargetTryptophan 2,3-dioxygenase(Human)
Iomet Pharma

US Patent
LigandPNGBDBM311863(US10155972, Compound Incyte 1)
Affinity DataIC50: 398nMAssay Description:In two separate assays, 0.045 μg/μl of human IDO protein was pre-incubated for 10 min at RT with test compounds NewLink 1 and Incyte 1 in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Iomet Pharma

US Patent
LigandPNGBDBM311863(US10155972, Compound Incyte 1)
Affinity DataIC50: 2.51E+3nMAssay Description:In two separate assays, 2.5 μg/μl of human TDO protein was pre-incubated for 10 minutes at RT with test compounds 680C91 and LM10 in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent