BDBM311952 US10166214, Example 88::US10675268, Example 88

SMILES Cc1cccc2c(ncnc12)C(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12

InChI Key InChIKey=WNWXLHSKHQGJRW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 311952   

TargetSomatostatin receptor type 4(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311952(US10166214, Example 88 | US10675268, Example 88)
Affinity DataEC50:  0.800nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2021
Entry Details
US Patent

TargetSomatostatin receptor type 4(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311952(US10166214, Example 88 | US10675268, Example 88)
Affinity DataEC50:  0.800nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent