BDBM311956 US10166214, Example 92::US10675268, Example 92

SMILES Cc1cccc2c(noc12)C(C)(C)NC(=O)[C@@H]1[C@H]2CNC[C@@H]12

InChI Key InChIKey=DEWGUMCLXFSVQC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 311956   

TargetSomatostatin receptor type 4(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311956(US10166214, Example 92 | US10675268, Example 92)
Affinity DataEC50:  0.400nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetSomatostatin receptor type 4(Human)
Centrexion Therapeutics

US Patent
LigandPNGBDBM311956(US10166214, Example 92 | US10675268, Example 92)
Affinity DataEC50:  0.400nMAssay Description:The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2021
Entry Details
US Patent