BDBM312233 US9604926, Compound AZ-66::US9724435, Compound AZ-66

SMILES CC(CCCn1c2ccc(F)cc2sc1=O)N1CCN(CC1)C1CCCCC1

InChI Key InChIKey=AXVCFARJNXIHLD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 312233   

TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University of Mississippi

US Patent
LigandPNGBDBM312233(US9604926, Compound AZ-66 | US9724435, Compound AZ...)
Affinity DataKi:  0.310nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
The University of Mississippi

US Patent
LigandPNGBDBM312233(US9604926, Compound AZ-66 | US9724435, Compound AZ...)
Affinity DataKi:  0.310nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Mus musculus (Mouse))
The University of Mississippi

US Patent
LigandPNGBDBM312233(US9604926, Compound AZ-66 | US9724435, Compound AZ...)
Affinity DataKi:  1.76nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
The University of Mississippi

US Patent
LigandPNGBDBM312233(US9604926, Compound AZ-66 | US9724435, Compound AZ...)
Affinity DataKi:  1.76nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent