BDBM3123 2-pyridinone deriv. 29::3-{[(2-ethoxyphenyl)methyl]amino}-5-ethyl-6-methyl-1,2-dihydropyridin-2-one

SMILES CCOc1ccccc1CNc1cc(CC)c(C)[nH]c1=O

InChI Key InChIKey=RDVNKJOMUQXXHJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3123   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM3123(3-{[(2-ethoxyphenyl)methyl]amino}-5-ethyl-6-methyl...)
Affinity DataIC50: 350nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2004
Entry Details Article
PubMed