BDBM31285 BMCL163310 Compound 1::CHEMBL361103::benzodiazepinedione, 1
SMILES OC(=O)[C@@H](N1[C@@H](c2ccc(Cl)cc2)C(=O)Nc2ccc(I)cc2C1=O)c1ccc(Cl)cc1
InChI Key InChIKey=HQEQUYKKMMKSSX-PMACEKPBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 31285
Affinity DataKd: 80nMpH: 7.5 T: 23°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMpH: 7.5 T: 23°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
Affinity DataKd: 80nMAssay Description:Displacement of fluorescein-labeled p53 peptide from HDM2 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Binding affinity to human HDM2More data for this Ligand-Target Pair
Affinity DataKd: 67nMAssay Description:Binding affinity to human HDM2More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Binding affinity between MDM2 and p53 protein in fluorescence peptide assayMore data for this Ligand-Target Pair