BDBM312956 3-[1-(2,6-Difluorobenzyl)-5-fluoro-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-yl]-7,7-dimethyl-5,7-dihydro-6H-pyrrolo[2,3-e][1,2,4]triazin-6-one::US9605008, 15

SMILES Cc1nc2n(Cc3c(F)cccc3F)nc(-c3nnc4c(NC(=O)C4(C)C)n3)c2cc1F

InChI Key InChIKey=RYIMMSRTDQPLAJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312956   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312956(US9605008, 15 | 3-[1-(2,6-Difluorobenzyl)-5-fluoro...)
Affinity DataIC50: 67nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent