BDBM312958 3-[5-Fluoro-1-(3-fluoro-4-methylbenzyl)-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-yl]-7,7-dimethyl-5,7-dihydro-6H-pyrrolo[2,3-e][1,2,4]triazin-6-one::US9605008, 17

SMILES Cc1ccc(Cn2nc(-c3nnc4c(NC(=O)C4(C)C)n3)c3cc(F)c(C)nc23)cc1F

InChI Key InChIKey=GDIZFTMMNBNFTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312958   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312958(US9605008, 17 | 3-[5-Fluoro-1-(3-fluoro-4-methylbe...)
Affinity DataIC50: 8nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent