BDBM312962 3′-[1-(2-Fluoro-4-methylbenzyl)-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-yl]spiro[cyclopropane-1,7′-pyrrolo[2,3-e][1,2,4]triazin]-6′(5′H)-one::US9605008, 22

SMILES Cc1ccc(Cn2nc(-c3nnc4c(NC(=O)C44CC4)n3)c3ccc(C)nc23)c(F)c1

InChI Key InChIKey=MCRMBCXJOPICJC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312962   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
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US Patent
LigandPNGBDBM312962(US9605008, 22 | 3′-[1-(2-Fluoro-4-methylbenz...)
Affinity DataIC50: 16nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent