BDBM313612 N-(5-(6-ethoxy-5- (tetrahydro-2H-pyran-4- yl)pyridazin-3-yl)-4- methylphenyl)-6- (trifluoromethyl) pyridazine-4-carboxamide::US10167279, Example 237

SMILES CCOc1nnc(cc1C1CCOCC1)-c1cc(NC(=O)c2cnnc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=WGSGBMHEAJWXLX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313612   

LigandChemical structure of BindingDB Monomer ID 313612BDBM313612(N-(5-(6-ethoxy-5- (tetrahydro-2H-pyran-4- yl)pyrid...)
Affinity DataIC50: 100nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent