BDBM313757 US10167285, Example 2

SMILES Clc1ccc(Cl)c(SC2Nc3cncnc3N2CCCC#C)c1Cl

InChI Key InChIKey=WMLDEBUCIQYIRM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 313757   

TargetHeat shock protein HSP 90-alpha(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313757(US10167285, Example 2)
Affinity DataEC50:  8.50E+3nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313757(US10167285, Example 2)
Affinity DataIC50: 4.84E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313757(US10167285, Example 2)
Affinity DataIC50: 5.80E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent