BDBM313894 US10167296, Example 2.05

SMILES COc1c(C)c2c(Nc3ccc(F)cc3O[C@H](C)C(=O)N[C@@H](C)C(F)(F)F)ncnc2cc1N=S1(=O)CCCC1

InChI Key InChIKey=RNSPDPHEMGBBDH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313894   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Evotec International

US Patent
LigandPNGBDBM313894(US10167296, Example 2.05)
Affinity DataIC50: 2.5nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent