BDBM313911 US10167296, Example 2.22

SMILES COc1c(C)c2c(Nc3ccc(F)cc3O[C@H]3CC[C@H](O)CC3)ncnc2cc1N=S(C)(C)=O

InChI Key InChIKey=RUSCZPZHSUNCMD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313911   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Evotec International

US Patent
LigandPNGBDBM313911(US10167296, Example 2.22)
Affinity DataIC50: 2.5nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent