BDBM313934 US10167296, Example 2.45

SMILES CO[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)Oc1cc(F)ccc1Nc1ncnc2cc(N=S(C)(C)=O)c(OC)c(C)c12

InChI Key InChIKey=KECYTGQDOMZAAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 313934   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Evotec International

US Patent
LigandPNGBDBM313934(US10167296, Example 2.45)
Affinity DataIC50: 1.70nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Evotec International

US Patent
LigandPNGBDBM313934(US10167296, Example 2.45)
Affinity DataIC50: 17nMAssay Description:The Z′-LYTE biochemical assay employs a fluorescence-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent