BDBM31440 phenylaminoethyl guanidine deriv., 21be

SMILES NC(=N)NCCNc1ccc(cc1-c1ccccc1)C(=O)Nc1ccc(cc1)N(Cc1ccc(F)cc1)Cc1ccc(F)cc1

InChI Key InChIKey=BZBVQTFJBASJIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31440   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Yale University

LigandPNGBDBM31440(phenylaminoethyl guanidine deriv., 21be)
Affinity DataIC50: 5.50E+4nMpH: 7.2 T: 2°CAssay Description:A bead-based FP assay methodology, termed IMAP, has been developed for the serine/threonine kinase, AKT that allows for direct measurement of product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2009
Entry Details Article
PubMed