BDBM314643 N-((1-aminoisoquinolin-6-yl)methyl)-2-((7- chloroquinolin-3-yl)methyl)isonicotinamide::US9611252, Example 139

SMILES Nc1nccc2cc(CNC(=O)c3ccnc(Cc4cnc5cc(ccc5c4)C#N)c3)ccc12

InChI Key InChIKey=OLZHWXPPOPYAAI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 314643   

TargetPlasma kallikrein(Human)
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM314643(N-((1-aminoisoquinolin-6-yl)methyl)-2-((7- chloroq...)
Affinity DataIC50: 100nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent