BDBM314760 US9611265, Ex. 3-49

SMILES COc1cc(ccc1OCc1ccc(cc1)C(F)(F)F)C(C)n1c(N)nc2cc(cnc12)-c1cnn(C)c1

InChI Key InChIKey=GJQVPMWSXKFICV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 314760   

TargetHigh affinity nerve growth factor receptor(Human)
Genzyme

US Patent
LigandPNGBDBM314760(US9611265, Ex. 3-49)
Affinity DataIC50: 0.300nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Genzyme

US Patent
LigandPNGBDBM314760(US9611265, Ex. 3-49)
Affinity DataIC50: 0.600nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

LigandPNGBDBM314760(US9611265, Ex. 3-49)
Affinity DataIC50: 19nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent