BDBM315256 (−) 3-{3-[(cyclobutyl{3-fluoro-4-[6-methyl-5-(trifluoromethyl)pyridin-3-yl]phenyl}acetyl)amino]-2-methylphenyl}propanoic acid, Single Enantiomer::US10172814, Example 206

SMILES Cc1ncc(cc1C(F)(F)F)-c1ccc(cc1F)C(C1CCC1)C(=O)Nc1cccc(CCC(O)=O)c1C

InChI Key InChIKey=SNJVXEVRMWGISW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315256   

TargetProstaglandin G/H synthase 2(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM315256((−) 3-{3-[(cyclobutyl{3-fluoro-4-[6-methyl-5...)
Affinity DataIC50: 10.1nMAssay Description:Recombinant proteins (human isoforms) of PTGES containing a FLAG tag, expressed in baculovirus infected insect cells (Hi-5) and purified by affinity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent