BDBM315257 3-[3-({cyclobutyl[3-fluoro-4-(5-isobutylpyridin-3-yl)phenyl]acetyl}amino)-2-methylphenyl]propanoic acid, Single Enantiomer::US10172814, Example 207

SMILES CC(C)Cc1cncc(c1)-c1ccc(cc1F)C(C1CCC1)C(=O)Nc1cccc(CCC(O)=O)c1C

InChI Key InChIKey=CBQWOUFQYNLUTC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 315257   

TargetProstaglandin G/H synthase 2(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM315257(3-[3-({cyclobutyl[3-fluoro-4-(5-isobutylpyridin-3-...)
Affinity DataIC50: 14.1nMAssay Description:Recombinant proteins (human isoforms) of PTGES containing a FLAG tag, expressed in baculovirus infected insect cells (Hi-5) and purified by affinity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent