BDBM315909 US10172859, Example 333::US11065253, Example 333::US9732094, Example 333::[4-Fluoro-3-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]thieno[2,3-d}- pyridazin-4-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.84 (d,J = 0.6, 1H), 9.08 (s, 1H), 8.28 (d, J = 5.3, 1H), 7.89(dd, J = 5.4, 0.7, 1H), 7.75-7.67 (m, 2H), 7.49 (dd,J = 9.4, 2.4, 1H), 7.45 (dd, J = 9.4, 2.9, 1H), 7.42-7.34 (m, 1H), 7.19 (d, J = 2.3, 1H), 6.82 (s, 1H),6.42 (s, 1H), 3.81-3.75 (m, 4H), 3.47-3.41 (m,4H).
SMILES OC(c1ccc(F)c(c1)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2sccc12
InChI Key InChIKey=AHYKWBDALRQZLR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 315909
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 ug of DNA-PK/protein complex and 100 ng of ...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Method for the detection and characterisation of test substances which interfere with the Kv11.1 (hERG) channel: Kv11.1 (hERG, human ether a-go-go re...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:The patch-clamp measurement was carried out at room temperature in whole-cell configuration on human embryonic kidney cells (HEK293) which have been ...More data for this Ligand-Target Pair