BDBM315912 US10172859, Example 336::US11065253, Example 336::US9732094, Example 336::[2,4-Difluoro-5-(7- morpholin-4-yl- quinazolin-4-yl)- phenyl]furo[2,3-d}- pyridazin-7-yl- methanol1H NMR (500 MHz, DMSO-d6) ppm = 9.63 (s,1H), 9.14 (s, 1H), 8.41 (d, J = 2.1, 1H), 8.10 (t,J = 8.1, 1H), 7.63 (dd, J = 9.4, 3.0, 1H), 7.58 (dd,J = 9.4, 2.5, 1H), 7.45 (t, J = 10.1, 1H), 7.27-7.19(m, 2H), 6.82 (d, J = 5.3, 1H), 6.63 (d, J = 5.3, 1H),3.83-3.77 (m, 4H), 3.50-3.45 (m, 4H).
SMILES OC(c1cc(c(F)cc1F)-c1ncnc2cc(ccc12)N1CCOCC1)c1nncc2ccoc12
InChI Key InChIKey=JFAVIPWOVRTGDI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 315912
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 ug of DNA-PK/protein complex and 100 ng of ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The kinase assay was carried out in streptavidin-coated 348-well microtitre flashplates. To this end, 1.5 μg of DNA-PK/protein complex and 100 n...More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Method for the detection and characterisation of test substances which interfere with the Kv11.1 (hERG) channel: Kv11.1 (hERG, human ether a-go-go re...More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:The patch-clamp measurement was carried out at room temperature in whole-cell configuration on human embryonic kidney cells (HEK293) which have been ...More data for this Ligand-Target Pair