BDBM316156 2-{[3-({5-[3-(2,5,8,11,14-pentaoxahexadecane-16-yl)ureido]pyridine-3-yl}ethynyl)-1H-indazol-6-yl]thio}-N-methylbenzamide ::US9617222, Compound 31

SMILES CNC(=O)c1ccccc1Sc1ccc2c(n[nH]c2c1)C#Cc1cncc(NC(=O)NCCOCCOCCOCCOCCOC)c1

InChI Key InChIKey=PLMWFMWZIOXTFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316156   

TargetVascular endothelial growth factor receptor 2(Human)
Senju Pharmaceutical

US Patent
LigandPNGBDBM316156(2-{[3-({5-[3-(2,5,8,11,14-pentaoxahexadecane-16-yl...)
Affinity DataIC50: 15nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent