BDBM316231 2-Methoxy-N4-[6-(2-methoxy-phenyl)-pyrimidin-4-yl]-benzene-1,4-diamine::US10294218, Example 59::US9617225, Example 59

SMILES COc1cc(Nc2cc(ncn2)-c2ccccc2OC)ccc1N

InChI Key InChIKey=HGSMVNIIHBGJNM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 316231   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Virostatics

US Patent
LigandPNGBDBM316231(US9617225, Example 59 | 2-Methoxy-N4-[6-(2-methoxy...)
Affinity DataIC50: 1.00E+3nMAssay Description:The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Virostatics

US Patent
LigandPNGBDBM316231(US9617225, Example 59 | 2-Methoxy-N4-[6-(2-methoxy...)
Affinity DataIC50: 1.00E+3nMAssay Description:The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Virostatics

US Patent
LigandPNGBDBM316231(US9617225, Example 59 | 2-Methoxy-N4-[6-(2-methoxy...)
Affinity DataIC50: 1.00E+3nMAssay Description:The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Virostatics

US Patent
LigandPNGBDBM316231(US9617225, Example 59 | 2-Methoxy-N4-[6-(2-methoxy...)
Affinity DataIC50: 1.00E+3nMAssay Description:The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent