BDBM316290 US10294218, Example 118::US9617225, Example 118::{5-[6-(4-Fluoro-2-methoxy-phenyl)-pyrimidin-4-ylamino]-2-methoxy-phenyl}-carbamic acid methyl ester

SMILES COC(=O)Nc1cc(Nc2cc(ncn2)-c2ccc(F)cc2OC)ccc1OC

InChI Key InChIKey=KBYKSVQSFWZBRT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 316290   

TargetCyclin-dependent kinase 9(Human)
Virostatics

US Patent
LigandPNGBDBM316290({5-[6-(4-Fluoro-2-methoxy-phenyl)-pyrimidin-4-ylam...)
Affinity DataIC50: 1.00E+3nMAssay Description:The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Virostatics

US Patent
LigandPNGBDBM316290({5-[6-(4-Fluoro-2-methoxy-phenyl)-pyrimidin-4-ylam...)
Affinity DataIC50: 1.00E+3nMAssay Description:The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Virostatics

US Patent
LigandPNGBDBM316290({5-[6-(4-Fluoro-2-methoxy-phenyl)-pyrimidin-4-ylam...)
Affinity DataIC50: 1.00E+3nMAssay Description:The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Virostatics

US Patent
LigandPNGBDBM316290({5-[6-(4-Fluoro-2-methoxy-phenyl)-pyrimidin-4-ylam...)
Affinity DataIC50: 1.00E+3nMAssay Description:The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent