BDBM316472 US9617246, 4::methyl 4-iodo-2-{[(3R,6R)-6-methyl- 1-{[2-(2H-1,2,3-triazol-2- yl)phenyl]carbonyl}piperidin-3- yl]sulfanyl}pyridine-3-carboxylate

SMILES COC(=O)c1c(I)ccnc1S[C@@H]1CC[C@@H](C)N(C1)C(=O)c1ccccc1-n1nccn1

InChI Key InChIKey=BMDNWMWUDQMCBG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 316472   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM316472(methyl 4-iodo-2-{[(3R,6R)-6-methyl- 1-{[2-(2H-1,2,...)
Affinity DataIC50: 23.6nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM316472(methyl 4-iodo-2-{[(3R,6R)-6-methyl- 1-{[2-(2H-1,2,...)
Affinity DataIC50: 54.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details
US Patent