BDBM316479 US9617246, 13::methyl 2-{[(3R,6R)-6-methyl-1- {[2-(2H-1,2,3-triazol-2- yl)phenyl]carbonyl}piperidin-3- yl]sulfanyl}pyridine-4-carboxylate

SMILES COC(=O)c1ccnc(S[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1

InChI Key InChIKey=STFILHBGMHKDEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 316479   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM316479(methyl 2-{[(3R,6R)-6-methyl-1- {[2-(2H-1,2,3-triaz...)
Affinity DataIC50: 297nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM316479(methyl 2-{[(3R,6R)-6-methyl-1- {[2-(2H-1,2,3-triaz...)
Affinity DataIC50: 6.31E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2019
Entry Details
US Patent