BDBM316851 US9617260, Compound 10::benzyl N-[3- [3-[(3,3- dimethyl-2- oxobutanoyl) amino]phenyl]- 1H- pyrrolo[2,3- b]pyridin-5- yl]carbamate

SMILES CC(C)(C)C(=O)C(=O)Nc1cccc(c1)-c1c[nH]c2ncc(NC(=O)OCc3ccccc3)cc12

InChI Key InChIKey=DKNNIIFDIBEKBN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316851   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM316851(US9617260, Compound 10 | benzyl N-[3- [3-[(3,3- di...)
Affinity DataIC50: 100nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Fluoresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent