BDBM316859 (3- fluorophenyl) methyl N-[3- [3-[2- (trifluoromethyl) prop-2- enoylamino] phenyl]-1H- pyrrolo[2,3- b]pyridin-5- yl]carbamate::US9617260, Compound 18

SMILES Fc1cccc(COC(=O)Nc2cnc3[nH]cc(-c4cccc(NC(=O)C(=C)C(F)(F)F)c4)c3c2)c1

InChI Key InChIKey=CBGCLKSBBFTUNR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316859   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM316859(US9617260, Compound 18 | (3- fluorophenyl) methyl ...)
Affinity DataIC50: 123nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Fluoresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent