BDBM316871 (3- cyanophenyl) methyl N-[3-[1- (2- oxopropanoyl)- 3,6-dihydro- 2H-pyridin-4- yl]-1H- pyrrolo[2,3- b]pyridin-5- yl]carbamate::US9617260, Compound 29

SMILES CC(=O)C(=O)N1CCC(=CC1)c1c[nH]c2ncc(NC(=O)OCc3cccc(c3)C#N)cc12

InChI Key InChIKey=VCOUWVLYWBJKHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316871   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM316871(US9617260, Compound 29 | (3- cyanophenyl) methyl N...)
Affinity DataIC50: 700nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Fluoresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent