BDBM316874 US9617260, Compound 32::propan-2-yl N- [3-(1-prop-2- enoylpiperidin- 4-yl)-1H- pyrrolo[2,3- b]pyridin-5- yl]carbamate

SMILES CC(C)OC(=O)Nc1cnc2[nH]cc(C3CCN(CC3)C(=O)C=C)c2c1

InChI Key InChIKey=ZANLIINCDFGGLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316874   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM316874(US9617260, Compound 32 | propan-2-yl N- [3-(1-prop...)
Affinity DataIC50: 27nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Fluoresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent