BDBM316875 US9617260, Compound 33::benzyl N-[3- (1-prop-2- enoyl-3,4- dihydro-2H- pyridin-5-yl)- 1H- pyrrolo[2,3- b]pyridin-5- yl]carbamate

SMILES C=CC(=O)N1CCCC(=C1)c1c[nH]c2ncc(NC(=O)OCc3ccccc3)cc12

InChI Key InChIKey=UOEUCAOTUZENSX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316875   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM316875(US9617260, Compound 33 | benzyl N-[3- (1-prop-2- e...)
Affinity DataIC50: 0.600nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Fluoresence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent