BDBM316967 6-Methoxy-pyridine-3- sulfonic acid [2,4-difluoro-3- (4-methoxy-7H-pyrrolo[2,3- d]pyrimidine-5-carbonyl)- phenyl]-amide::US9617267, Compound P-1018

SMILES COc1ccc(cn1)S(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncnc(OC)c23)c1F

InChI Key InChIKey=SORRSVSKYMCMAT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 316967   

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Plexxikon

US Patent
LigandPNGBDBM316967(US9617267, Compound P-1018 | 6-Methoxy-pyridine-3-...)
Affinity DataIC50: 100nMAssay Description:Assays for biochemical and cell based activity are known in the art, for example, as described in PCT publication WO 2007/002433, the disclosure of w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Plexxikon

US Patent
LigandPNGBDBM316967(US9617267, Compound P-1018 | 6-Methoxy-pyridine-3-...)
Affinity DataIC50: 100nMAssay Description:Assays for biochemical and cell based activity are known in the art, for example, as described in PCT publication WO 2007/002433, the disclosure of w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandPNGBDBM316967(US9617267, Compound P-1018 | 6-Methoxy-pyridine-3-...)
Affinity DataIC50: 100nMAssay Description:Assays for biochemical and cell based activity are known in the art, for example, as described in PCT publication WO 2007/002433, the disclosure of w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent