BDBM317549 3-(3-(3-(2,4- difluorophenyl)ureido)-4- (diisobutylamino)phenyl)- 4,4,4-trifluorobutanoic acid::US9624188, 30

SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1ccc(F)cc1F)C(CC(O)=O)C(F)(F)F

InChI Key InChIKey=LLRWXYAXYSABOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 317549   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM317549(US9624188, 30 | 3-(3-(3-(2,4- difluorophenyl)ureid...)
Affinity DataIC50: 0.700nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM317549(US9624188, 30 | 3-(3-(3-(2,4- difluorophenyl)ureid...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human IDO1 in HEK293 cells after 20 hrs by plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed