BDBM318034 8-Methyl-2-[4-[[3-trifluoromethyl)-2- pyridyl]methyl]piperazin-1-yl]- 3,5,6,7-tetrahydropyrido[2,3- d]pyrimidin-4-one dihydrochloride::US9624218, Example 35::US9624218, Example 36
SMILES CN1CCCc2c1nc([nH]c2=O)N1CCN(Cc2ccccc2C(F)(F)F)CC1
InChI Key InChIKey=VLKQIEMXMFAOES-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 318034
Affinity DataIC50: 21.6nMAssay Description:The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...More data for this Ligand-Target Pair
Affinity DataIC50: 7.54nMAssay Description:The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...More data for this Ligand-Target Pair
Affinity DataIC50: 9.57E+4nMAssay Description:The Poly ADP-ribose polymerase 1(PARP1) assay is an ELISA which detects poly ADP ribose incorporated into plate-bound histone protein in a 384-well f...More data for this Ligand-Target Pair
Affinity DataIC50: 17.6nMAssay Description:The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...More data for this Ligand-Target Pair
Affinity DataIC50: 26.2nMAssay Description:The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...More data for this Ligand-Target Pair