BDBM318213 US10301317, Example 169::US9624228, Example 169

SMILES CC(C)CCN1CCC[C@H](C1)N1Cc2cc3c(n[nH]c3cc2NC1=O)-c1ccnc(C)c1

InChI Key InChIKey=VMTUEJIHLGAIBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318213   

TargetMitogen-activated protein kinase 1(Human)
Kura Oncology

US Patent
LigandPNGBDBM318213(US9624228, Example 169 | US10301317, Example 169)
Affinity DataIC50: 50nMAssay Description:The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Kura Oncology

US Patent
LigandPNGBDBM318213(US9624228, Example 169 | US10301317, Example 169)
Affinity DataIC50: 50nMAssay Description:The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
US Patent