BDBM318241 US9624228, Example 197

SMILES CC(c1ccc(F)cc1)c1cc2cc3c(n[nH]c3cc2[nH]c1=O)-c1ccnc(C)c1

InChI Key InChIKey=VHCYLFUSEVYJGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 318241   

TargetMitogen-activated protein kinase 1(Human)
Kura Oncology

US Patent
LigandPNGBDBM318241(US9624228, Example 197)
Affinity DataIC50: 50nMAssay Description:The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent