BDBM318423 (2S,4R)-4-(2,2-diphenylacetyl)-4-(methyl(3-phenylprop-2-yn-1-yl)amino)piperidine-2-carboxylic acid::US9624234, 32

SMILES CN(CC#Cc1ccccc1)[C@@]1(CCN[C@@H](C1)C(O)=O)C(=O)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=TWGAPEWNEMTZJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 318423   

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM318423((2S,4R)-4-(2,2-diphenylacetyl)-4-(methyl(3-phenylp...)
Affinity DataIC50: 108nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent