BDBM318598 N-{[(4S)-7-(3,5-Dimethylisoxazol- 4-yl)-2-oxo-4-pyridin-2-yl-1,2,4,5- tetrahydroimidazo[1,5,4- de][1,4]benzoxazin- 9-yl]methyl}-N'-isopropylurea::US10464947, Example 142::US9624241, Example 142
SMILES CC(C)NC(=O)NCc1cc(-c2c(C)noc2C)c2OC[C@H](c3ccccn3)n3c2c1[nH]c3=O
InChI Key InChIKey=DAQFIOVDWLOROM-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 318598
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair