BDBM318599 2-(Dimethylamino)-N-{[(4S)-7- (3,5-dimethylisoxazol-4-yl)-2- oxo-4-pyridin-2-yl-1,2,4,5- tetrahydroimidazo[1,5,4- de][1,4]benzoxazin-9- yl]methyl}acetamide::US10464947, Example 143::US9624241, Example 143
SMILES CN(C)CC(=O)NCc1cc(-c2c(C)noc2C)c2OC[C@H](c3ccccn3)n3c2c1[nH]c3=O
InChI Key InChIKey=OITUTHADDQJXOF-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 318599
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...More data for this Ligand-Target Pair