BDBM318764 1-((2R,3S)-2-(hydroxymethyl)-3-(3-phenylpropoxy)-azetidin-1-yl)-2,2-diphenylethanone and 14(2S,3R)-2-(hydroxymethyl)-3-(3-phenylpropoxy)-azetidin-1-yl)-2,2-diphenylethanone::US10370388, Compound 143::US9624243, 56

SMILES OC(=O)[C@H]1[C@@H](CN1C(=O)C(c1ccccc1)c1ccccc1)OCCCc1ccccc1

InChI Key InChIKey=YVHCQCFELZHKAG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318764   

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM318764(1-((2R,3S)-2-(hydroxymethyl)-3-(3-phenylpropoxy)-a...)
Affinity DataIC50: 316nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM318764(1-((2R,3S)-2-(hydroxymethyl)-3-(3-phenylpropoxy)-a...)
Affinity DataIC50: 372nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent