BDBM318799 (2S,4S)-N-(N,N-dimethylsulfamoyl)-1-(2,2-diphenylacetyl)-4-(3-phenylpropoxy)pyrrolidine-2-carboxamide::US9624243, 112

SMILES CN(C)S(=O)(=O)NC(=O)[C@@H]1C[C@@H](CN1C(=O)C(c1ccccc1)c1ccccc1)OCCCc1ccccc1

InChI Key InChIKey=NPFUOBKNVTUWIO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 318799   

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM318799(US9624243, 112 | (2S,4S)-N-(N,N-dimethylsulfamoyl)...)
Affinity DataIC50: 255nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent