BDBM318800 (2S,4S)-N-(N,N-dimethylsulfamoyl)-1-(2,2-diphenylacetyl)-4-((3-(4-fluorophenyl)propyl)(methyl)amino)pyrrolidine-2-carboxylic acid::US9624243, 114

SMILES CN(C)S(=O)(=O)NC(=C)[C@@H]1C[C@@H](CC1C(=O)C(c1ccccc1)c1ccccc1)N(C)CCCc1ccc(F)cc1

InChI Key InChIKey=MDWWIRKBZJZHEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 318800   

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM318800(US9624243, 114 | (2S,4S)-N-(N,N-dimethylsulfamoyl)...)
Affinity DataIC50: 17.1nMAssay Description: 120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent