BDBM319081 US10173991, Example 124::methyl N-{4-[4- chloro-2- ({[(cyclopropyl- carbamoyl)methyl] carbamoyl} (methanesulfonyl) methyl)-1,3- benzothiazol- 6-yl]-2- fluorophenyl} carbamate

SMILES CS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2c(Cl)cc(cc2s1)-c1ccc(NC(=O)CO)c(F)c1

InChI Key InChIKey=NGHYHURCLGTPHJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 319081   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM319081(US10173991, Example 124 | methyl N-{4-[4- chloro-2...)
Affinity DataIC50: 2nMAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
Entry Details
US Patent