BDBM319484 US10173991, Example 540::propan-2-yl N-{4- [2-({[(cyclopropyl- carbamoyl)methyl] carbamoyl}(2- methoxyethane- sulfonyl)methyl)- 5-fluoro-1,3- benzothiazol- 6-yl]phenyl} carbamate

SMILES CC(C)OC(=O)Nc1ccc(cc1)-c1cc2sc(nc2cc1F)C(C(=O)NCC(=O)NC1CC1)S(=O)(=O)CCCO

InChI Key InChIKey=KTPSMQSSYLSDNF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 319484   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM319484(propan-2-yl N-{4- [2-({[(cyclopropyl- carbamoyl)me...)
Affinity DataIC50: 2nMAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent