BDBM319499 US10173991, Example 555::benzyl N-(3-{2- [(cyclopropane- sulfonyl) ({[(cyclopropyl- carbamoyl)methyl] carbamoyl}) methyl]-5-fluoro- 1,3-benzothiazol- 6-yl}phenyl) carbamate

SMILES Fc1cc2nc(sc2cc1-c1cccc(NC(=O)OCc2ccccc2)c1)C(C(=O)NCC(=O)NC1CC1)S(=O)(=O)C1CC1

InChI Key InChIKey=UIEIBCGPRGYODE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 319499   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM319499(benzyl N-(3-{2- [(cyclopropane- sulfonyl) ({[(cycl...)
Affinity DataIC50: 1nMAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent